Aeon Technology Inc.

TEAM-FF

TEAM-FF stands for Transferable, Extensible, Accurate and Modular force field. Several novel and patent-pending techniques make TEAM-FF outstanding from traditional force fields. It is not only a database that contains large number of high quality force field parameters, but also an open database that can be easily extended by adding force field parameters or force fields.

A key concept is that TEAM-FF contains multiple force fields that can be used together. That means parameters can be taken from different tables even though the force fields are independently developed. The quality of mixing depends on how those force fields are developed. Since nonbond interaction (VDW and electrostatic) terms are generally transferable using the common (e.g. Lorentz-Berthelot) combining rules, the default is to mix nonbond terms only.

TEAM-FF contains a set of native force fields that provide the base-level support. In addition, external force fields with special coverage are included. Currently the standard tables are:

T_TEAM
T_AMBER, AMBER+
T_CHARMM
T_CFF
T_DREIDING

The T_XXXX tables are native force fields developed based on the same ab initio data but cast into different force field types. These force fields have great coverage of organic molecules, polymers and drug-like compounds. AMBER+ is a force field developed based on AMBER99 with additional parameters added to cover more variations of proteins.

Aeon Technology Inc.
9823 Pacific Heights Blvd, Suite F, San Diego, CA 92121
Tel: 858-964-0869 Fax: 858-677-0240
Email: info@AeonTechnology.com